Synthetic Biology for Naval Applications
This program aims to extend the natural capabilities of living organisms (such as microbes) by using synthetic biology to create systems that will provide new naval capabilities. The potential to design purpose-specific organisms — for environmental sensing and information processing, or, for production of electronic materials and devices — is attractive as a platform technical approach. Note that this program is not interested in mammalian cell engineering, biomedical applications, or metabolic engineering to produce fuels/pharmaceuticals.
Research Concentration Areas
- Environmental Surveillance
- Synthetic Microbial Electronics
Research Challenges and Opportunities
- Fundamental research is needed to understand and exploit unique regulatory control, and sensing elements, particularly for microbe-mineral or microbe-metal interactions
- Research is also needed to understand the microbial genetics, physiology and respiratory processes that control the morphology and composition of biogenic mineral/metal nanomaterials and structures
- Strategies to shorten the cellular sense-to-response interval are needed to enable practical applications (e.g., avoiding genetically-encoded responses dependent on transcription/translation)
- Applied research is needed to integrate engineered microbes with complementary metal oxide semiconductor (CMOS) or optoelectronic interfaces to enable monitoring of seawater (or other media) for analytes of interest (e.g., organic/inorganic pollutants, energetic materials, pathogens or their toxins)
- Research directed at integrating living, engineered cells into autonomous systems to enable bi-directional communication and control is also desired
Program Contact Information
Submit white papers, QUAD charts and full proposals for contracts to this email address: ONR Code 34 Research Submissions
Follow instructions within BAA for submission of grant proposals to grants.gov website.