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The Composites Manufacturing Technology Center (CMTC), established in 2000, is located in Anderson, SC, and is operated by the Applied Research and Development Institute of the South Carolina Research Authority (SCRA).

The Penn State University Electro-Optics Center (EOC) was established in 1999 as the Navy’s Center of Excellence for Electro-Optics.

The Electronics Manufacturing Center (EMC) was established in 2021 to identify, develop and facilitate the transition of electronics manufacturing technologies to reduce the cost and time to deploy electrical and electronic (digital and analog) systems as well as the supporting power storage and distribution infrastructure to naval ships, aircraft, submarines and unmanned systems.

The Energetics Manufacturing Technology Center (EMTC), established in 1994, is Navy operated and located at the Naval Sea Systems Command's Naval Surface Warfare Center, Indian Head Explosive Ordnance Disposal Technology Division (NSWC IHEODTD), Indian Head, Maryland.

The Institute for Manufacturing and Sustainment Technologies (iMAST), established in 1995, coordinates Navy ManTech efforts at The Pennsylvania State University’s Applied Research Laboratory (ARL), one of four U.S. Navy University Affiliated Research Centers (UARCs).

The Naval Shipbuilding and Advanced Manufacturing Center develops advanced technologies and deploys them in U.S. industrial facilities to improvement manufacturing process and reduce costs.

The Office of Naval Research's Metamaterials program supports basic research on optical and acoustic metamaterials to control light and sound propagation over a large frequency range.

The Office of Naval Research's Acoustic Transduction Materials and Devices program supports basic and applied research on materials and device technologies for Navy applications that generate, detect and suppress undersea signal for navigation, threat detection, weapons guidance, communication and the like.

The Office of Naval Research's Materials & Processes for Additive Manufacturing (AM) program is focused on exploring new and novel approaches in developing and understanding AM materials and manufacturing processes for naval applications.

Naval assets, large and small, spend months to years at sea exposed to considerable biofouling pressures. The Office of Naval Research's Biofouling Control program sponsors research to develop antifouling/fouling release coatings and the mechanics underlying such materials.