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The Office of Naval Research's Quantum Information Science program focuses on developing underlying science and technology for the application of quantum systems to information process tasks that include computing and communication.

The Office of Naval Research's Operational Endurance from Environmental Carbon program seeks technology development to support sustainable carbon neutral operational energy processes and materials for U.S. Navy and U.S. Marine Corps needs.

The Office of Naval Research's CAST program seeks to develop technologies to enable cooperative operations of unmanned maritime systems including unmanned underwater vehicles (UUVs), unmanned surface vessels (USVs) and weapons in a wide range of mission areas.

The Space Sensor & Effects objective is to develop and experiment with key technology enablers that provide effective and resilient Intelligence, Surveillance, Reconnaissance & Targeting (ISRT) capabilities as affordable and proliferated space-borne sensors for littoral & maritime environments.

The aim of the Biotechnology for Naval Applications Program is to discover and develop biologically based and bioengineered solutions to expand current Warfighter capabilities in the domains of materials, manufacturing, electronics, sensors, and devices.

The aim of Undersea Medicine & Performance is to develop improved methods, models, treatments and devices for understanding, preventing or mitigating factors that negatively impact divers and submariners.

The Office of Naval Research's Ship Signatures program supports the Navy’s interest in advanced sea platform survivability science and technology, and submarine science and technology.